Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
During the cuprizone diet, myelin genes were strongly downregulated at all time points compared to controls (a). On day 6, no obvious decrease in the staining intensity was observed in the LFB-PAS staining (b) nor in the CNPase immunohistochemistry (c). After 21 days of cuprizone diet, a markedly increased cellularity was associated with a slightly patchy LFB-PAS staining (d) whereas the CNPase staining revealed no signs of demyelination (e).
