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. 2015 Feb 13;29(5):291–299. doi: 10.1016/j.blre.2015.02.001

Fig. 2.

Fig. 2

Risks of major TTVs linked to interventions, and accelerating rate of EIDs of concern to blood safety.

Evolution of the risks of transmission by blood transfusion for HIV, HBV, and HCV. Major interventions to reduce risks are indicated below the time line on the X axis. Emerging infectious disease threats over the past 20 years are indicated above in the top right quadrant of the figure. Ab = antibody; Ag = antigen; CHIKV = Chikungunya virus; DENV = dengue virus; ICL = idiopathic CD4 + T-lymphocytopenia; SARS = severe acute respiratory syndrome; SFV = simian foamy virus; XMRV = xenotropic murine leukemia virus-related virus.

Reproduced with permission, from Perkins, et al. Transfusion 2010;50:2080–2099.