Table 2.

Variations observed in the aa sequence of the HE glycoproteins of BCoV field strains compared to that of the reference Mebus strain^a

Amino acid	Pathology and strains
EBCoV strains							RBCoV strains
NCD					WD
Mebus (HRT)	Mebus (FBK)	BCoV.Que (MDBK)	BCQ.571 (HRT)	BCQ.1523 (HRT)	BCQ.2590 (HRT)	BCQ.7373 (HRT)	OK-0514 (HRT)	BCO 43277 (HRT)	BCO 44175 (HRT)	BCQ 3994 (HRT)
5	L	*	*	P	P	P	p	p	p	p	p
8	V	*	*	*	*	A	*	*	*	*	*
11	S	*	*	*	C	*	*	*	*	*	*
49	N	*	*	*	T	*	T	T	T	T	T
53	R	*	*	*	*	P	*	*	*	*	*
66	D	*	*	*	*	*	*	G	G	G	G
139	V	*	*	*	*	*	*	G	*	*	*
182	G	*	*	*	*	*	R	*	*	*	*
245	F	*	*	*	*	*	L	*	*	*	*
282	D	*	*	*	*	*	G	*	*	*	*
344	D	*	*	*	*	A	*	*	*	*	*
350	Q	*	*	*	*	R	*	*	*	*	*
367	S	*	*	P	P	P	P	P	P	P	P
392	L	*	*	I	I	*	I	I	I	I	I
394	L	*	*	*	*	*	*	*	*	F	*
400	G	*	*	*	*	*	*	S	*	*	*

^aAn asterisk (*) indicates a consensus with the reference Mebus strain.