Table 1.

Properties of polyclonal immune serum globulin products currently marketed in the United States

Product	Manufacturer	IgG concentration	IgA concentration	Excipients	Viral safety
Products intended for intravenous use
Carimmune NF	CSL-Behring	powdera	0.72 mg/mL	sucrose	low pH, pepsin, 35 nm NF
Flebogamma DIF	Grifols	5%	< 0.05 mg/mL	50 mg/mL sorbitol; < 3 mg/mL PEG	pasteurization, S/D, 20 nm NF
Gammagard S/D	Baxter	powderb	< 2.2 μg/mL	3 mg/mL albumin; 22.5 mg/mL glycine; 20 mg/mL glucose; 2 mg/mL PEG; 8.5 mg/mL NaCl	S/D
Gammagard Liq.	Baxter	10%	37 μg/mL	250 mM glycine	pH 4, S/D, NF
Gamunex	Talecris	10%	46 μg/mL	200 mM glycine	pH4, caprylate
Octagam	Octapharma	5%	< 0.2 mg/mL	10% maltose	S/D, pH 4
Privigen	CSL-Behring	10%	< 25 μg/mL	250 mM L-proline	pH4, NF
Products intended for subcutaneous use
Vivaglobin	CSL-Behring	16%	< 1.7 mg/mL	0.3 g/L NaCl	pasteurization
				250 mM glycine	fatty alcohol/low pH
Products Intended for intramuscular use
Gamastan	Talecris	16%	NL	300 mM glycine	S/D

Abbreviations: NF, nanofiltered; NL, not listed; PEG, polyethylene glycol; S/D, solvent/detergent.

^aMay be reconstituted to 3%, 6%, 9%, or 12% solution.

^bMay be reconstituted to 5% or 10% solution. Data given for 5% solution.