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. 2011 Dec 14;32(1):89–95. doi: 10.1016/j.bios.2011.11.037

Table 1.

Comparison of characteristics of PCR and isothermal amplification reactions.

LAMP PCR SDA NASNA RCA bDNA Invader
Target amplification + + + + +
Signal amplification + + + +
Isothermal + + + + + +
Sensitivity (copies/ml) >10 >10 500 100 1 500 6000
Multiplex amplification + + + +
Detection method Turbidimetry and Fluorometry Fluorometry Fluorometry Fluorometry Fluorometry Luminescence assay Fluorometry
Enzyme linked immunoassay