Table 2.
Pulmonary protein/mRNA expression of Col-I, iNOS and TGF-β1in 5-group rats (Mean ± S.D.)
| NC | PC | HC | CH | CL | |
|---|---|---|---|---|---|
| Protein | |||||
| Col-I | 0.62 ± 0.12 | 1.34 ± 0.11*** | 0.81 ± 0.19### | 0.92 ± 0.27## | 0.90 ± 0.09## |
| iNOS | 0.74 ± 0.12 | 1.83 ± 0.23*** | 1.27 ± 0.41## | 1.26 ± 0.42## | 1.25 ± 0.16## |
| TGF-β1 | 0.74 ± 0.35 | 4.26 ± 0.43*** | 1.52 ± 0.21### | 1.07 ± 0.28### | 0.81 ± 0.23### |
| mRNA | |||||
| Col-I | 225.15 ± 153.30 | 614.87 ± 208.70** | 295.56 ± 158.34# | 262.68 ± 126.00# | 255.22 ± 293.67## |
| iNOS | 7.62 ± 1.70 | 47.46 ± 18.20*** | 23.30 ± 3.28## | 9.87 ± 3.88### | 24.97 ± 21.70# |
| TGF-β1 | 19.55 ± 6.58 | 122.68 ± 39.10*** | 27.39 ± 11.33### | 31.61 ± 8.80### | 25.85 ± 4.04### |
ANOVA indicated intra-group differences for the proteins of Col-I (F = 12.261, P < 0.001), iNOS (F = 8.388, P < 0.001) and TGF-β1 (F = 112.979, P < 0.001), and mRNA of Col-I (F = 3.329, P < 0.05), iNOS (F = 7.605, P < 0.001) and TGF-β1 (F = 26.258, P < 0.001). LSD comparison showed a significant difference between two groups: ***P < 0.001 and **P < 0.01 vs. the Group NC, respectively; ###P < 0.001, ##P < 0.01 and #P < 0.05 vs. the Group PC, respectively.