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. 2009 Dec 30;28(9):2088–2096. doi: 10.1016/j.vaccine.2009.12.038

Table 2.

Neutralization antibody titer in murine sera.

Vaccine Dose (PFU) Routea IC50 IC90
MVTTZCI 106 i.m. 23.8 22.3
104 i.m. <2 <2
106 i.n. 24.8 21
104 i.n. <2 <2



VTTb 106 i.m. 26.1 22.7
104 i.m. 24.5 21.8
a

i.m., intramuscular inoculation; i.n., intranasal inoculation.

b

Since VTT kills mice via i.n., the i.n. Nab titer was not determined in this group. Neutralization antibody titer was calculated by determining the highest serum dilution (1:2 serial dilution) to achieve 50% or 90% viral inhibition.