Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Mar 13;23(9):2555–2559. doi: 10.1016/j.bmcl.2013.02.117

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Published by Elsevier Ltd.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Scheme 3 — Synthesis of 2-f luoro-2-deoxy-arabinose-1-phosphate prodrugs. (a) HBr, DCM, rt, 13 h, (b) Et₃N, H₂O, DMF, rt, 1.5 h, 100% over two-steps, (c) TIPS-OTf, 2,6-lutidine, CH₂Cl₂, 0 °C, 2.5 h, 100%, (d) Et₃N, H₂O, MeOH, rt, 3 days, 86%, (e) CbzCl, DMAP, CH₂Cl₂, rt, 12 h, 95%, (f) HF-pyr, pyridine, rt, 44 h, 100%, (g) appropriated phosphorochloridate, tBuMgCl, THF, rt, 15 h, (h) H₂, Pd/C, EtOH, rt, 2 h.