Table 3.
Requirements for ordering multiplex molecular panels and comments included in report to facilitate interpretation
| Panel | Requirement/Recommendations for Ordering | Comments |
|---|---|---|
| RVP | Recommended in immunosuppressed patients with high risk for respiratory complications, and patients with severe respiratory infections that need to be admitted | No test of cure, no repeats of negatives unless new symptoms Encourage no testing or use the rapid flu test if influenza is suspected |
| GIP | Community-acquired diarrhea of ≥7 d duration, travel-related diarrhea, severe presentation (bloody diarrhea, dehydration), immunocompromised status, or norovirus suspected | No test of cure, no repeats of negatives The following comment is included in each report: “No antimicrobial therapy is recommended for mild illness with symptoms <7 d” |
| MEP | High suspicion of infectious meningitis/encephalitis CSF with signs compatible with infectious process and at least 50 WBCs |
If suspecting HSV, order the stand-alone HSV, which has higher sensitivity Culture must be ordered at the same time Likelihood of false positive, correlate with other tests and clinical presentation |
Abbreviations: CSF, cerebrospinal fluid; GIP, gastrointestinal panel; HSV, herpes simplex virus; MEP, meningitis/encephalitis panel; RVP, respiratory viral panel; WBC, white blood cells.