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. 2019 Dec 10;34(1):51–65. doi: 10.1016/j.idc.2019.10.006

Table 3.

Requirements for ordering multiplex molecular panels and comments included in report to facilitate interpretation

Panel Requirement/Recommendations for Ordering Comments
RVP Recommended in immunosuppressed patients with high risk for respiratory complications, and patients with severe respiratory infections that need to be admitted No test of cure, no repeats of negatives unless new symptoms
Encourage no testing or use the rapid flu test if influenza is suspected
GIP Community-acquired diarrhea of ≥7 d duration, travel-related diarrhea, severe presentation (bloody diarrhea, dehydration), immunocompromised status, or norovirus suspected No test of cure, no repeats of negatives
The following comment is included in each report: “No antimicrobial therapy is recommended for mild illness with symptoms <7 d”
MEP High suspicion of infectious meningitis/encephalitis
CSF with signs compatible with infectious process and at least 50 WBCs
If suspecting HSV, order the stand-alone HSV, which has higher sensitivity
Culture must be ordered at the same time
Likelihood of false positive, correlate with other tests and clinical presentation

Abbreviations: CSF, cerebrospinal fluid; GIP, gastrointestinal panel; HSV, herpes simplex virus; MEP, meningitis/encephalitis panel; RVP, respiratory viral panel; WBC, white blood cells.