Table 6.
Examples of comments included in the antimicrobial susceptibility testing report
| Organism/Specimen | Comment |
|---|---|
| Haemophilus influenzae isolated from sterile sites | H influenzae is considered susceptible to ceftriaxone and meropenem even if β-lactamase positive. |
| H influenza and Haemophilus parainfluenza from respiratory specimens | H influenzae may produce β-lactamase, which causes resistance to penicillin, ampicillin, and amoxicillin. However, H influenzae is generally susceptible to amoxicillin-clavulanate, cefuroxime, cefpodoxime, cefdinir, ceftriaxone, and azithromycin even if β-lactamase positive. |
| Group B streptococcus from vaginal/rectal swab for screening pregnant women | Group B streptococci are universally susceptible to ampicillin, penicillin, and cefazolin and testing is not necessary. If the clindamycin is reported as susceptible, the result has been confirmed by D test, and the organisms should be considered susceptible to clindamycin. |
|
Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis from clean-catch urine Cefazolin breakpoints for urine are applied |
In the treatment of uncomplicated urinary tract infections, cefazolin susceptibility predicts susceptibility to the oral cephalosporins cephalexin, cefuroxime, cefpodoxime, and cefdinir. Cephalexin is cost-effective, but QID dosing (normal renal function) is less convenient than the other oral cephalosporins, which are dosed BID. Isolates resistant to cefazolin but susceptible to ceftriaxone may be susceptible to cefpodoxime. |
| Carbapenem-resistant enterobacteriaceae | Based on additional testing the following comment is added: carbapenamase-producing organism. Consult AS team for treatment recommendations. |