Table I.

Change in rhinovirus-induced inflammatory mediators after dexamethasone treatment of BEC cultures

	Dexamethasone, 10 nmol/L	Dexamethasone, 100 nmol/L	Dexamethasone, 1000 nmol/L
IP-10	−12.4 (−46.4 to 0.81)	−55.9∗ (−72.5 to −32.1)	−97.9∗ (−99 to −96.4)
RANTES	−63.7∗ (−87 to −46)	−88.8∗ (−90.7 to −80.5)	−97.1∗ (−98.9 to −95.3)
IL-6	−50.3∗ (−69.9 to −31.4)	−87.5∗ (−93.2 to −77.7)	−95.9∗ (−98.8 to −89.7)
IL-8	−38.1∗ (−58.1 to −15.1)	−74∗ (−83.9 to −25.3)	−84.2∗ (−94.4 to −65.4)
TNF-α	−2.7 (−28.8 to 0.4)	−14∗ (−30.5 to −4)	−57.4∗ (−69.7 to −34.2)

All values are expressed as the percentage change from primary BECs infected with rhinovirus alone. Primary BECs were treated for 24 hours before infection with dexamethasone (10, 100, or 1000 nM).

^∗Significant reduction compared with rhinovirus-infected primary BECs (P < .01, Wilcoxon signed-rank test).