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. 2008 Jan 4;20(7):1227–1236. doi: 10.1016/j.cellsig.2007.12.018

Fig. 2.

Fig. 2

Capsid proteins localize to intracellular sites that are not related to virus assembly. West Nile virus (WNV) and Rubella virus (RV) both replicate in the cytoplasm and assemble on membranes of the endoplasmic reticulum and Golgi complex respectively. However, large pools of their capsid proteins localize to the nucleous (WNV) or mitochondria (RV). Cells were infected with WNV (upper panels) or RV (lower panels) and then fixed and processed for indirect immunofluorescence. Nuclei were stained with DAPI and mitochondria were detected with antibodies specific for the matrix protein p32.