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Numbers of hydrophobic contacts between residues of SARS-CoV Mpro and group I compounds in the S4–S1 binding mode
| Residues | Number of hydrophobic contacts |
||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| Leu141 | 1 | ||||
| Asn142 | 1 | ||||
| Cys145 | 1 | 2 | 1 | 1 | |
| Met165 | 12 | 10 | 11 | 10 | 13 |
| Glu166 | 5 | 2 | 4 | 2 | 3 |
| Leu167 | 5 | 7 | 5 | 4 | 5 |
| Pro168 | 1 | 1 | 1 | 1 | |
| Gln189 | 3 | 3 | 4 | 3 | 2 |
| Gln192 | 2 | 1 | |||
| Total | 27 | 26 | 28 | 21 | 25 |
