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. 2017 Aug 9;42:275–281. doi: 10.1016/j.jcrc.2017.07.038

Table 2.

Clinical characteristics of patients with Zika virus infection in intensive care.

Patients 1 2 3 4 5 6 7 8 9 10
ICU characterization
Mean APACHE II (standard deviation) 12 ± 7



Reason for ICU admission — no (%)
Risk of respiratory insufficiency caused by neuromuscular weakness 6 (60) + + + + + +
Progressive neurological deterioration (motor/sensitive) 0 (0) +
Mental status compromise 3 (30) +
Other (septic shock/thrombocytopenia) 1 (10) + +



Indicators of stay. Median-IQR (days)
Time: Begging of symptoms-ICU admission 5.5 (9–2) 1 0 18 4 6 2 8 5 22 9
Time: Hospital stay 13 (14–3) 36 3 10 9 14 25 7 9 11 10
Time: ICU stay 6.5 (9–6) 0 3 6 6 16 27 7 9 9 6
Time: Begging of symptoms − Neurological nadir 6 (8–4) 4 3 7 8 5 8 14 5
Rankin at discharge 1 (6–1) 5 1 1 6 6 1 1



Hemodynamic support n (%)
Need for ventilatory support 6 (60) + + + + + +
Need for hemodynamic support 4 (40) + + + +
Plasmapheresis 1 (10) +
Immunoglobulins 6 (60) + + + + + +

PCR: Polymerase Chain Reaction, IgM: Immunoglobulin M, APACHE = acute physiology and chronic health examination, ICU: Intensive Care Unit, IQR: Interquartile range.