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. 2017 Dec 29;36(3):557–576. doi: 10.1016/j.biotechadv.2017.12.016

Table 2.

Basic characteristics of RNA viruses.

RNA viruses
Genom
Replication
Virus family RNA type/segment/topology Polarity Enzyme Intracellular site
Arenaviridae ssRNA/2/linear Ambisense Virion RNA polymerase Cytoplasm
Arteriviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm
Astroviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm
Birnaviridae dsRNA/2/linear both Virion RNA polymerase Cytoplasm
Bornaviridae ssRNA/1/linear (−) Virion RNA polymerase Nucleus
Bunyaviridae ssRNA/3/linear (−) or ambisense Virion RNA polymerase Cytoplasm
Caliciviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm
Coronaviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm
Deltavirus ssRNA/1/circular (−) RNA polymerase II Nucleus
Filoviridae ssRNA/1/linear (−) Virion RNA polymerase Cytoplasm
Flaviviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm
Hepeviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm
Nodaviridae ssRNA/2/linear (+) Viral RNA polymerase Cytoplasm
Orthomyxoviridae ssRNA/6-8/linear (−) Virion RNA polymerase Nucleus
Paramyxoviridae ssRNA/1/linear (−) Virion RNA polymerase Cytoplasm
Picornaviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm
Reoviridae dsRNA/10-12/linear both Virion RNA polymerase Cytoplasm
Retroviridae ssRNA/2/linear (+) Virion reverse transcriptase Nucleus/cytoplasm
Rhabdoviridae ssRNA/1/linear (−) Virion RNA polymerase Cytoplasm
Togaviridae ssRNA/1/linear (+) Viral RNA polymerase Cytoplasm