Table 1.
Number of active compounds of structures A–C on susceptible viruses and range of their EC50
| Virusa | No. of active aminoazocompounds (A–C) over 12 tested compoundsb | No. of active compounds (range of EC50, μM) | ||
|---|---|---|---|---|
| Reo-1c | 1 | / | 1 (12) | / |
| HSV-1d | 2 | 1 (6) | 1 (12) | / |
| BVDVe | 7 | 5 (1, 6–9) | 1 (16) | 1 (30) |
| YFVe | 4 | 3 (7–10) | 1 (12) | / |
| RSVf | 1 | / | / | 1 (25) |
| CVB-2e | 1 | / | 1 (11) | / |
a
HIV-1, VSV, VV and Sb-1 were unaffected by all tested compounds of structure A–C.
b
Compounds with EC50 > 100 μM, or higher than CC50 for the host cells are considered inactive.
c
Double stranded RNA virus.
d
DNA virus.
e
Single-stranded, positive RNA virus.
f
Single-stranded, negative RNA virus.