Table 2.

Number of active compounds of structures D–G on susceptible viruses and range of their EC₅₀

Virusa	No. of active triazene derivatives (D–G) over 46 tested compoundsb	No. of active compounds (range of EC50, μM)
Reo-1c	3	/	/	1 (30)	1 (33)	1 (80)
Sb-1d	7	/	1 (15)	3 (25–30)	2 (42, 44)	1 (51)
HSV-1e	6	/	3 (12–14)	1 (30)	/	2 (55, 64)
BVDVd	2	/	1 (19)	/	/	1 (90)
YFVd	5	/	1 (20)	2 (23, 24)	1 (50)	1 (80)
RSVf	11	6 (3–10)	3 (15–20)	/	/	2 (60, 73)
CVB-2d	12	4 (6–10)	3 (12–14)	2 (25, 30)	2 (35, 50)	1 (71)

^aHIV-1, VSV and VV were unaffected by all tested compounds of structure D–G.

^bCompounds with EC₅₀ > 100 μM, or higher than CC₅₀ for the host cells are considered inactive.

^cDouble stranded RNA virus.

^dSingle-stranded, positive RNA virus.

^eDNA virus.

^fSingle-stranded, negative RNA virus.