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. 2008 Jan 11;16(7):4138–4149. doi: 10.1016/j.bmc.2008.01.011

Table 1.

Chemical structure, physiochemical properties, and SARS-3CLpro inhibitory activity of the identified hits

Compound ID Chemical structure MW C log P SARS-3CLpro activity
% Inh. at 10 μM IC50 (μM)
PJ07 graphic file with name fx2.gif 381.49 4.50 30 18.2
PJ169 graphic file with name fx3.gif 453.58 4.78 40 17.2