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. 2019 Apr 10;102(6):4857–4869. doi: 10.3168/jds.2018-16016

Figure 6.

Figure 6

Mechanism of action of hyperimmune bovine colostrum (HBC)-derived IgG, untreated colostrum, or ammonium sulfate (AS) supernatant on rotavirus strains. Panels a, b, and c show the effect of HBC-derived IgG on Wa, HRV248, and NCDV, respectively, binding to the MA104 cell surface. Panels d, e, and f show the results of virus inactivation assays on infectious particles of Wa, HRV248, and NCDV, respectively. On the y-axis, the infectious titers of HRoV are expressed as focus-forming units per milliliter (FFU/mL). Error bars represent the SEM of independent experiments. *P < 0.05, **P < 0.001, ***P < 0.0001. HRoV = human rotavirus; BRoV = bovine rotavirus.