Table 3.
Comparison of Treatment Outcomes Between Patients Receiving Combined iSI and Phacoemulsification versus Phacoemulsification Alone
| Univariate Analysis of Outcomes Between Intervention Groups† | |||
|---|---|---|---|
| iStent® Inject and Phacoemulsification | Phacoemulsification | p | |
| Number of eyes | 63 | 59 | − |
| Number of Medications^ ~ | |||
| Overall | 0.3 ± 0.9 | 0.1 ± 0.6 | − |
| For patients on medication at baseline | 0.6 ± 1.0 | − | − |
| Intraocular Pressure in mmHg (% Change from Baseline) | |||
| 1 day | 17.1 ± 7.6 (+8.2) | 13.4 ± 4.8 (−2.2) | 0.15 |
| 1 week | 15.7 ± 5.4 (−0.6) | 13.3 ± 6.0 (−2.9) | 0.01* |
| 4 weeks | 15.2 ± 4.0 (−3.8) | 12.4 ± 3.5 (−9.5) | <0.001* |
| 6 months | 13.5 ± 3.2 (−14.6) | 11.4 ± 2.5 (−16.8) | 0.002* |
| 12 months | 11.4 ± 2.6 (−27.8) | 13.3 ± 3.4 (−2.9) | 0.35 |
| 18 months | 14.6 ± 2.5 (−7.6) | 9.8 ± 1.3 (−28.5) | 0.02* |
| 24 months | 12.7 ± 3.8 (−19.6) | 12.6 ± 5.1 (−8.0) | 0.65 |
| Best corrected visual acuity in logMAR (Change from baseline) | 0.1 ± 0.2 (−0.1) | 0.0 ± 0.1 (−0.1) | 0.608 |
| Spherical equivalent in D~ (Change from baseline) | −0.3 ± 0.5 (+0.9) | −0.5 ± 0.5 (−1.5) | >0.99 |
Notes: †Presented as [mean ± SD] unless otherwise specified. –Not applicable. ^Anti-glaucoma medication. ~After 4 weeks. *Denotes significance at p < 0.05. Number (n); p-value (p); standard deviation (SD)