Table 2.
Comparison of Remitters vs Non-Remittors
| Variables | Total | Non-Remitters | Remitters | p value |
|---|---|---|---|---|
| N | 3130 | 1823 | 1307 | |
| Age of onset (years): mean±SD | 34.7±12.5 | 33.5±12.0 | 36.2±13.0 | <0.001 |
| Personality disorders: n (%) | 181 (5.8) | 148 (8.1) | 32 (2.4) | <0.001 |
| Pervasive developmental disorders: n (%) | 207 (6.6) | 148 (8.1) | 59 (4.5) | <0.001 |
| Alcohol/substance abuse: n (%) | 167 (5.3) | 133 (7.3) | 34 (2.6) | <0.001 |
| Physical comorbidity: n (%) | 968 (30.9) | 557 (30.6) | 411 (31.4) | 0.601 |
| Rapid cycling: n (%) | 329 (10.5) | 264 (14.5) | 65 (5.0) | <0.001 |
| Social function: n (%) | <0.001 | |||
| Global Assessment of Functioning 81–100 | 1008 (32.2) | 203 (11.1) | 805 (61.6) | |
| Global Assessment of Functioning 61–80 | 1407 (45.0) | 972 (53.3) | 435 (33.3) | |
| Global Assessment of Functioning 41–60 | 606 (19.4) | 550 (30.2) | 56 (4.3) | |
| Global Assessment of Functioning 1–40 | 87 (2.8) | 81 (4.4) | 6 (0.5) | |
| Pharmacological treatment: n (%) | 3104 (99.2) | 1811 (99.3) | 1293 (98.9) | 0.147 |
| Mood stabilizers: n (%) | ||||
| Lithium | 1488 (47.5) | 783 (43.0) | 705 (53.9) | <0.001 |
| Valproic acid | 893 (28.5) | 533 (29.2) | 358 (27.4) | 0.259 |
| Carbamazepine | 149 (4.8) | 97 (5.3) | 52 (4.0) | 0.082 |
| Lamotrigine | 744 (23.8) | 481 (26.4) | 263 (20.1) | <0.001 |
| Antipsychotics: n (%) | 1692 (54.1) | 1081 (59.3) | 611 (46.7) | <0.001 |
| Antidepressants: n (%) | 1291 (41.2) | 828 (45.4) | 463 (35.4) | <0.001 |
| Anxiolytics: n (%) | 1133 (36.2) | 739 (40.6) | 394 (30.2) | <0.001 |
| Hypnotics: n (%) | 1886 (60.3) | 1213 (66.5) | 673 (51.5) | <0.001 |