Fig. 17.

DNA nanotweezers-regulated enzyme reaction. a A G6PDH/NAD⁺ pair. Reproduced from Liu et al. [48], with permission. Copyright 2013, Springer Nature. b A GOx/HRP cascade. Reproduced from Xin et al. [143], with permission, copyright 2013, John Wiley and Sons. c A three-component biocatalytic cascade of β-Gal/GOx/hemin. Reproduced from Hu et al. [144], with permission, copyright 2014, John Wiley and Sons. d Distance regulation of a GOx/HRP pair. Reproduced from Kou et al. [145], with permission, copyright 2018, American Chemical Society. e A trident-shaped DNA nanomachine with several conformational states for regulating an enzyme cascade. Reproduced from Xing et al. [146], with permission, copyright 2018, American Chemical Society