Fig. 5.

In vivo assembly of enzyme cascades on RNA nanostructures. a Organization of [FeFe]-hydrogenase and ferredoxin on one-dimensional (1D) and 2D RNA nanostructures (top) with enhanced hydrogen production in vivo (bottom). Reproduced from Delebecque et al. [85], with permission, copyright 2011, The American Association for the Advancement of Science. b Assembly of a two-enzyme pentadecane production pathway on RNA scaffolds (top) with enhanced pentadecane output in vivo (bottom). Reproduced from Sachdeva et al. [86], with permission, copyright 2014, Oxford University Press