Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 10;47(1):20–33. doi: 10.5653/cerm.2020.00388

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020. THE KOREAN SOCIETY FOR REPRODUCTIVE MEDICINE

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 6. — (A) Representative photomicrographs showing normal histology and histopathology. (a) Control group; normal arrangement of spermatogenic and Sertoli cells. (b-h) Histopathological findings of the seminiferous tubules found in the type 1 and type 2 diabetes mellitus (T1DM and T2DM) groups. (b) Sloughing of deciduous and spermatogenic cells (arrows) into the tubular lumen. (c) Cell with large nuclei (arrow) in the seminiferous epithelium. (d) Cell with small nuclei and vacuolization (arrow) in the seminiferous epithelium. (e) Few spermatogenic cell layers of artifactual sloughing (arrow) of germ cell elements into the lumen. (f) Vacuolization (arrows) of Sertoli cells and absence of spermatids. (g) Atrophy with germ cell degeneration and small vacuolization between spermatogonia and Sertoli cells. (h) Hypospermatogenesis with all germ layers diminished. (B) Seven histopathology types by percentage. Values are presented as mean ± standard deviation. C-T1DM, type 1 diabetes mellitus control; C-T2DM, type 2 DM control. ^a)p< 0.05 compared with controls; ^b)p< 0.05 compared with T2DM; ^c)p< 0.05 compared with T1DM.