TABLE II.
Animal groups and ultrasound imaging timepoints for plaque characterization. • denotes ultrasound timepoints, and “⊗” denotes ultrasound, PAT, and euthanize timepoints. PCL, partial carotid ligation; WD, Western diet.
| Purpose | Experimental groups | n | Imaging timepoints (days) | |||||
|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 4 | 7 | 10 | 14 | |||
| Lipid deposition over time | Day 7 post-PCL +WD | 8 | • | • | • | ⊗ | ||
| Day 10 post-PCL +WD | 8 | • | • | • | • | ⊗ | ||
| Day 14 post-PCL +WD | 8 | • | • | • | • | • | ⊗ | |
| Sham control +WD | 5 | • | • | • | • | • | ⊗ | |
| Strain predictor of lipid deposition | Day 4 post-PCL +WD | 5 | • | • | ⊗ | |||
| Day 4 post-PCL + chow | 6 | • | • | ⊗ | ||||