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Inhibition of Tumorigenesis by BRB in the oral cavity of DBP-treated mice.
| Treatments | ||
|---|---|---|
| DBP | DBP + BRB | |
| Number of mice | 30 | 30 |
| CIS | 4 (13.3)1 | 1 (3.3) |
| Papilloma | 10 (33.3)1 | 4 (13.3)* |
| SCC | 12 (40.0)1 | 10 (33.3) |
| Total Tumors | 21 (70.0)2 | 14 (46.7)* |
Number in parentheses, percentage of mice developed tumors.
Tumors induced by DBP in the oral cavity consist of papilloma, CIS and SCC.
Tumor incidence was significantly reduced compared to DBP treatment, p < 0.05.
