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. 2020 Mar 3;85(7):4648–4662. doi: 10.1021/acs.joc.9b03371

Scheme 7. Thiol–Disulfide Exchange Studies of ETP 42.

Scheme 7

Conditions: (a) para-fluorobenzylthiol, (para-fluorobenzyl)disulfane, NEt3, THF, 23 °C. (b) NaBH4, MeOH, THF; S-(phenylsulfonyl)-l-glutathione hydrogen chloride, NEt3, MeOH, THF, 23 °C. (c) l-Glutathione, NEt3, D2O, CD3CN, 23 °C.