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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Ticks Tick Borne Dis. 2019 Dec 14;11(3):101359. doi: 10.1016/j.ttbdis.2019.101359

Table 9.

Detailed results for studies with Borrelia burgdorferi sensu lato spirochetes to evaluate the vector competence of Amblyomma, Dermacentor, or Haemaphysalis ticks occurring in the Nearctic (NA), Palearctic (PA), Oriental (OR), or Australian (AU) zoogeographic regions.

Spirochete species and source/isolate Host used as source of infection for feeding ticks
Spirochete acquisition by ticks fed on hosts with active infection
Transstadial passage of spirochetes to molted ticks of the next life stage
Spirochete transmission by ticks fed on naïve hosts
Reference
Species Route of spirochete infection Life stage No. examined % infected Life stage No. examined % infected Life stage Host No. infected ticks known to have fed per hosth No. hosts known to have been exposed to at least 1 infected tickh No. hosts for which infection was confirmed after tick feeding
Amblyomma americanum (NA)
B. burgdorferi s.s. (JD1) Hamster Tick bited Larva 118 4f Nymph 218 0 Piesman and Sinsky, 1988
B. burgdorferi s.s. (JD1) P. leucopus b Tick bited Larva 16 19f Nymph 33 0 Mather and Mather, 1990
B. burgdorferi s.s. (JD1) White rabbit Needlee Larva 200 0f Nymph No data No data Nymph White rabbit No data No data 0 (out of 6)i Mukolwe et al., 1992
B. burgdorferi s.s. (B31) White mouse Tick bited Larva No data 0g Nymph No data 0 Soares et al., 2006
B. burgdorferi s.s. (NC-2) White mouse Needlee Larva 30 0g Nymph 40 0 Nymph White mouse 0 0 0 (out of 2)i Piesman and Happ, 1997
B. burgdorferi s.s. (SI-1) Hamster Needlee Larva No data No data Nymph No data No data Nymph Hamster No data No data 0 (out of 15)i Oliver et al., 1993
B. burgdorferi s.s. (SI-1) White mouse Needlee Larva 20 0g Nymph 10 0 Piesman and Happ, 1997
B. burgdorferi s.s. (SH2-82) Hamster Needlee Larva 36 19f Nymph 60 2 Nymph Hamster No data No data 0 (out of 3)i Ryder et al., 1992
B. bissettiae (MI-6) Hamster Needlee Larva No data No data Nymph 105 0 Nymph White mouse No data No data 0 (out of 23)i Sanders and Oliver, 1995
Dermacentor andersoni (NA)
B. burgdorferi s.l. (Wild)a White mouse Needlee Larva 90 17g Nymph 30 0 Nymph White mouse 0 0 0 (out of 2)i Dolan et al., 1997
B. burgdorferi s.s. (B31) White mouse Needlee Larva 90 11g Nymph 30 0 Nymph White mouse 0 0 0 (out of 2)i Dolan et al., 1997
Dermacentor mittalli (PA)
B. garinii (Wild) White mouse Needlee Larva No data 50f Nymph No data 0 Nymph White mouse No data No data 0j Sun et al., 2003a
B. garinii (Wild) White mouse Needlee Nymph No data 60f Adult No data 0 Adult White mouse No data No data 0j Sun et al., 2003a
Dermacentor occidentalis (NA)
B. burgdorferi s.l. (Wild)a Wild rodentsc Tick bitec Larva No data No data Nymph 44 0 Brown and Lane, 1992
B. burgdorferi s.s. (CA5) Hamster Tick bited Larva 20 10g Nymph 40 0 Lane et al., 1994
Dermacentor silvarum (PA)
B. garinii (Wild) White mouse Needlee Larva No data 40f Nymph No data 0 Nymph White mouse No data No data 0j Sun and Xu, 2003
B. garinii (Wild) White mouse Needlee Nymph No data 50f Adult No data 0 Adult White mouse No data No data 0j Sun and Xu, 2003
Dermacentor variabilis (NA/NT)
B. burgdorferi s.l. (MI-119)a White mouse Needlee Larva 23 61g Nymph 21 10 Piesman and Happ, 1997
B. burgdorferi s.l. (MI-128)a White mouse Needlee Larva 20 10g Nymph 10 0 Piesman and Happ, 1997
B. burgdorferi s.l. (MI-129)a White mouse Needlee Larva 30 37g Nymph 30 0 Nymph White mouse 0 0 0 (out of 18)i Piesman and Happ, 1997
B. burgdorferi s.s. (JD1) Hamster Tick bited Larva 49 14f Nymph 77 0 Piesman and Sinsky, 1988
B. burgdorferi s.s. (JD1) P. leucopus b Tick bited Larva 75 28f Nymph 150 0 Mather and Mather, 1990
B. burgdorferi s.s. (JD1) White rabbit Needlee Larva 200 0f Nymph No data No data Nymph White rabbit No data No data 0 (out of 6)i, k Mukolwe et al., 1992
B. burgdorferi s.s. (B31) White mouse Tick bited Larva No data >0g Nymph No data >0 Nymph White mouse No data No data 0j Soares et al., 2006
B. burgdorferi s.s. (NC-2) White mouse Needlee Larva 47 28g Nymph 49 2 Nymph White mouse 0 0 0 (out of 6)i Piesman and Happ, 1997
B. burgdorferi s.s. (SI-1) White mouse Needlee Larva 48 58g Nymph 30 0 Piesman and Happ, 1997
B. bissettiae (MI-6) Hamster Needlee Larva No data No data Nymph 105 0 Nymph White mouse No data No data 0 (out of 21)i Sanders and Oliver, 1995
Haemaphysalis concinna (OR/PA)
B. garinii (Wild) White mouse Needlee Larva No data 70–80f Nymph No data 0 Nymph White mouse No data No data 0j Sun and Xu, 2003
B. garinii (Wild) White mouse Needlee Nymph No data 70f Adult No data 0 Adult White mouse No data No data 0j Sun and Xu, 2003
Haemaphysalis longicornis (AU/NA/OR/PA)
B. garinii (Wild) White mouse Needlee Larva No data 60–70f Nymph No data 0 Nymph White mouse No data No data 0j Sun et al., 2003a
B. garinii (Wild) White mouse Needlee Nymph No data 60–70f Adult No data 0 Adult White mouse No data No data 0j Sun et al., 2003a
B. burgdorferi s.s. (B31) White mouse Tick bited Larva 32 56f Nymph 520 0 Breuner et al., 2020
a

Uncharacterized Borrelia burgdorferi sensu lato spirochetes.

b

Laboratory colony of white-footed mice (Peromyscus leucopus).

c

Field-collected and naturally tick-bite infected dusky-footed woodrats (Neotoma fuscipes) or California kangaroo rats (Dipodomys californicus).

d

Bite by infected I. scapularis ticks.

e

Inoculated with a suspension containing cultured spirochetes.

f

Larvae or nymphs harvested within 2 d after completing their blood meal.

g

Larvae or nymphs harvested within the first 2 wk after completing their blood meal.

h

By examination of either fed ticks or the resulting unfed ticks of the next life stage; or elucidated via transmission to uninfected ticks in a co-feeding experiment. Listed as no data when the number was not clearly stated in the publication.

i

The study presented no evidence that any naïve host was exposed to an infected tick.

j

The study presented no evidence that any naïve host was exposed to an infected tick, and the number of hosts used was not given.

k

One of these rabbits was seroreactive but no spirochetes were isolated from tissues (liver, spleen, heart, kidneys, and urinary bladder) taken at necropsy; the evidence for this rabbit was therefore not considered sufficient to conclude that infection was confirmed. In contrast, rabbits exposed to I. scapularis ticks infected with the same spirochete isolate in this study uniformly were both seroreactive and yielded tissues from which spirochetes were cultured.