Table 2.
Genotype frequencies in OSA and non-OSA subjects
| SNPs | Genotype | OSA group (N/%) N = 233 | Non-OSA group (N/%) sN = 93 | χ2 | Pa |
|---|---|---|---|---|---|
| rs1801282 | CC | 211 (90.56%) | 74 (79.57%) | 7.299 | 0.021* |
| CG | 22 (9.44%) | 19 (20.43%) | |||
| C | 444 (95.28%) | 167 (89.78%) | 6.089 | 0.027* | |
| G | 22 (4.72%) | 19 (10.22%) | |||
| rs3856806 | CC | 147 (63.09%) | 51 (54.84%) | 2.173 | 0.337 |
| CT | 80 (34.33%) | 38 (40.86%) | |||
| TT | 6 (2.58%) | 4 (4.30%) | |||
| C | 374 (80.26%) | 140 (75.27%) | 1.983 | 0.194 | |
| T | 92 (19,74%) | 46 (24.73%) | |||
| rs13073869 | GG | 96 (41.20%) | 41 (44.09%) | 5.810 | 0.111 |
| GA | 116 (49.79%%) | 36 (38.71%) | |||
| AA | 21 (9.01%) | 16 (17.20%) | |||
| G | 308 (66.09%) | 118 (63.44%) | 0.413 | 0.290 | |
| A | 158 (33.91%) | 68 (36.56%) |
Results are expressed as n (%). Differences between groups were analyzed by χ2 text or Fisher’s exact
OSA obstructive sleep apnea, SNPs single nucleotide polymorphisms, PaP value was adjusted by step-down Bonferroni
*P < 0.05