Table 4.
Multivariate logistic regression analyses of rs1801282 with the risk of OSA in stratified analysis according to obesity
| Genotype | Unadjusted | Model 1 | Model 2 | ||||
|---|---|---|---|---|---|---|---|
| OR (95CI) | P value | OR (95CI) | P value | OR (95CI) | P value | ||
|
Obesity N = 114 |
CC | 1 | 1 | 1 | |||
| CG | 0.188 (0.056–0.628) | 0.007* | 0.150 (0.039–0.580) | 0.006* | 0.166 (0.030–0.901) | 0.037* | |
|
Non-obesity N = 212 |
CC | 1 | 1 | 1 | |||
| CG | 0.447 (0.190–1.054) | 0.066 | 0.368 (0.139–0.977) | 0.045* | 0.345 (0.124–0.959) | 0.041* | |
Model 1: adjusted for age, sex, BMI, smoker and drinker. Model 2: adjusted for model 1 + TG, HDL-C, FBG and ESS
OSA obstructive sleep apnea, BMI body mass index, TG triglycerides, HDL-C high-density lipoprotein cholesterol, FPG fasting plasma glucose, ESS Epworth Sleepiness Scale
*P < 0.05