Table 2.
QoL and autonomy for activities of daily living in patients with 5-2-1 criteria (n = 20) vs those with 5-2-1 negative criteria (n = 82).
| 5-2-1 positive (n = 20) | 5-2-1 negative (n = 82) | p value | |
|---|---|---|---|
| PDQ-39SI | 25.6 ± 14 | 12.1 ± 9.2 | <0.0001 |
| Mobility | 32.1 ± 22.4 | 11.7 ± 17.7 | <0.0001 |
| Activities of daily living | 25.8 ± 15.3 | 12.1 ± 12 | <0.0001 |
| Emotional well-being | 29.1 ± 27.5 | 16.1 ± 18.9 | 0.014 |
| Stigma | 16.8 ± 32.4 | 6 ± 14.9 | 0.028 |
| Social support | 7.1 ± 16.5 | 2.5 ± 9.3 | 0.102 |
| Cognition | 22.2 ± 21 | 14.2 ± 15.8 | 0.060 |
| Communication | 2.9 ± 7.8 | 2.7 ± 7.7 | 0.927 |
| Pain and discomfort | 52.4 ± 26.6 | 29.8 ± 20.4 | <0.0001 |
| PQ-10 | 6.1 ± 2 | 7.1 ± 1.3 | 0.007 |
| EUROHIS-QOL8 | 3.5 ± 0.5 | 3.7 ± 0.4 | 0.034 |
| Quality of life | 3.4 ± 0.9 | 3.8 ± 0.6 | 0.024 |
| Health status | 3 ± 0.8 | 3.3 ± 0.7 | 0.069 |
| Energy | 3.6 ± 0.6 | 3.7 ± 0.6 | 0.452 |
| Autonomy for ADL | 2.9 ± 0.7 | 3.6 ± 0.6 | <0.0001 |
| Self-esteem | 3.6 ± 1.2 | 3.8 ± 0.7 | 0.313 |
| Social relationships | 3.9 ± 0.8 | 4 ± 0.5 | 0.657 |
| Economic capacity | 3.8 ± 0.6 | 3.8 ± 0.6 | 0.968 |
| Habitat | 4 ± 0.8 | 4.1 ± 0.5 | 0.452 |
| ADLS | 73.5 ± 13.1 | 89.2 ± 9.3 | <0.0001 |
| Functional dependency (%) | 45 | 7.3 | <0.0001 |
Chi-squared and Mann–Whitney–Wilcoxon tests were applied. ADLS, Schwab and England Activities of Daily Living Scale; PDQ-39SI, 39-Item Parkinson's Disease Quality of Life Questionnaire Summary Index.