Table 6.
Redox biomarkers of the nonenzymatic system in the homogenate of the thoracic aortic aneurysm patients with LDS and C subjects.
| Parameters (mg/protein) | C Median (Min–Max) |
LDS Median (Min–Max) |
p |
|---|---|---|---|
| TAC (nmol Trolox) | 119.6 (35–220) | 15.09 (0.38–145) | 0.006 |
| LPO index (nmol MDA) | 2.4 (0.53–7.4) | 5.7 (2.3–15) | 0.04 |
| Carbonylation (ng carbonyls) | 5.5 (2.04–11.8) | 10.4 (4.3–21.1) | 0.01 |
| GSH (nM) | 9 × 10−2 (1 × 10−3–6 × 10−2) | 8 × 10−3 (3 × 10−3–1 × 10−2) | 0.006 |
| NO3−/NO2− (nM) | 2.6 (1.97–4.3) | 3.37 (2.14–7.8) | NS |
| Vitamin C (μM) | 0.03 (0.02–0.04) | 0.02 (0.01–0.04) | 0.01 |
| Se (pg) | 119.6 (35–220) | 15.09 (0.38–145) | 0.01 |
Abbreviations: TAC: total antioxidant capacity; LPO: lipid peroxidation; GSH: glutathione; Se: selenium; LDS: Loeys-Dietz syndrome; C: control subjects. The data are presented as the median and Min–Max range.