Table 1.
Treatment groups | Treatment | |
---|---|---|
I | Normal control | Normal saline only (10 ml/kg bw; i.p) |
II | Negative control | Normal saline+scopolamine (1 mg/kg bw; i.p) |
III | Positive control | Donepezil (1 mg/kg bw; p.o)+scopolamine (1 mg/kg bw; i.p) |
IV | Experimental group 1 | Extract (50 mg/kg bw; p.o)+scopolamine (1 mg/kg bw; i.p) |
V | Experimental group 2 | Extract (100 mg/kg bw; p.o)+scopolamine (1 mg/kg bw; i.p) |
VI | Experimental group 3 | Extract (200 mg/kg bw; p.o)+scopolamine (1 mg/kg bw) |
All the administered drugs were prepared in normal saline (0.9% NaCl). Extract: aqueous/methanolic stem bark extracts of P. thonningii; p.o: oral administration; i.p: intraperitoneal administration.