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. 2002 Dec 3;25:3–12. doi: 10.1016/S1386-6532(02)00197-X

Table 1.

Bottlenecks in molecular diagnostics

Problem identified Possible solution
Quantitative technologies Real time amplification technologies
Internal and external control Well defined universal internal controls; Quality control programs
Sample preparation still matrix dependent New extraction technologies
Hands-on time and turn-around time results Automation
Commercially interesting viruses vs. viruses of no commercial interest Well characterized home-brew assays