Table 1.

Grading Criteria

Event	1	2	3	4	5
Infusion-related reaction	Mild reaction, infusion interruption not indicated, intervention not indicated	Therapy or infusion interruption indicated but responds promptly to symptomatic treatment	Prolonged (eg, not rapidly responsive to symptomatic medication and/or brief interruption of infusion), recurrence of symptoms after initial improvement	Life-threatening consequences, pressor or ventilatory support indicated, urgent intervention indicated	Death
Hypotension	Asymptomatic, intervention not indicated	Nonurgent medical intervention indicated	Medical intervention	Life-threatening and urgent intervention indicated	Death

Grading according to the Common Terminology Criteria for Adverse Events/Cancer Therapy Evaluation Program, version 4.0.