Skip to main content
. 2010 Jan 20;187(3):310–319. doi: 10.1016/j.tvjl.2009.12.022

Fig. 6.

Fig. 6

(a) Pulmonary lesions in the right cranial apical lung lobe of a pig 21 days after inoculation with PRRSV isolate VR-2332. Interstitial pneumonia with thickened interalveolar septa, septal infiltration of mononuclear cells (arrow, example), hypertrophy and hyperplasia of alveolar epithelial cells (arrowhead, example) and alveolar exudate (*, example). HE stain, bar = 200 μm. (b) Morphology of unaltered pulmonary tissue in the left cranial pulmonary lobe of a control pig 21 days after sham inoculation. Note open alveolar spaces and thin, even interalveolar septa due to intrapulmonary instillation of fixative. HE stain, bar = 200 μm. (c) Distribution of PRRSV antigen in the right cranial apical lung lobe of a pig 21 days post-inoculation with PRRSV isolate VR-2332. PRRSV antigen as shown by the presence of granular red reaction product is present in alveolar macrophages (arrowheads, examples) and in alveolar walls (arrows, examples). APAAP, bar = 100 μm.