Table 3.
Patient clinical data, stratified by age, and distributed by respiratory virus results
| Patient data: age ≤1 year | RSV | A/H1N1/2009 | RV | p‐value |
|---|---|---|---|---|
| N = 55 | N = 8 | N = 9 | ||
| Hospitalization (days): median (range) | 5 (3–27) | 5 (3–8) | 5 (4–15) | NS |
| Severity scorea: median (range) | 5 (0–8)b | 1 (1–3)b | 3 (0–5) | <0.05b |
| WBC >15 000/mm3, n (%) | 4/55 (7)c | 1/8 (12) | 4/9 (44)c | <0.05c |
| Lymphocytes (n/mm3), median (range) | 3850d (368–8418) | 4447d (2368–13 007) | 7901d (2772–35 552) | <0.05d |
| Neutrophils (n/mm3), median (range) | 3500 (507–20 600) | 2574 (608–8536) | 6105 (2298–18 564) | NS |
| Eosinophils (n/mm3), median (range) | 63e (4–638) | 28e (10–405) | 119e (55–1081) | <0.05e |
| CRP >0.8 mg/mL, n (%) | 16/55 (29) | 3/8 (37) | 5/9 (55) | NS |
| Patient data: age >1 year | RSV | A/H1N1/2009 | RV | p‐value |
|---|---|---|---|---|
| N = 23 | N = 8 | N = 7 | ||
| Hospitalization (days), median (range) | 5 (2–18) | 5 (4–23) | 4 (4–9) | NS |
| Severity scorea, median (range) | 3 (0–8)b | 0.5 (0–6)b | 3 (1–6) | 0.05b |
| WBC >15 000/mm3, n (%) | 5/23 (22)c | 2/8 (25) | 5/7 (71)c | <0.05c |
| Lymphocytes (n/mm3), median (range) | 2752 (803–7595) | 1058 (398–3819) | 2643 (681–5632) | NS |
| Neutrophils (n/mm3), median (range) | 5932c (1062–22 480) | 6186c (914–16 839) | 15 935c (8480–29 352) | <0.05c |
| Eosinophils (n/mm3), median (range) | 28 (0.1–291) | 26 (0.2–217) | 113 (8–224) | NS |
| CRP >0.8 mg/mL, n (%) | 9/23 (39) | 5/8 (62) | 4/7 (57) | NS |
A/H1N1/2009, pandemic A (H1N1) 2009 influenza virus; CRP, blood C‐reactive protein; NS, not significant; RSV, respiratory syncytial virus; RV, rhinovirus; WBC, white blood cell; only hospitalized patients with single infections were considered.
aAge‐adjusted severity score [6].
bRSV vs. A/H1N1/2009: p <0.05, calculated with Fisher’s exact test.
cRV vs. RSV: p <0.05, calculated with the Mann–Whitney U‐test.
dRSV vs. A/H1N1/2009 and RSV vs. RV: p <0.05, calculated with the Mann–Whitney U‐test.
eRV vs. RSV and RV vs. A/H1N1/2009: p <0.05, calculated with the Mann–Whitney U‐test.