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. 2015 Dec 28;12:S1–S110. doi: 10.1111/j.1470-9465.2006.12_4_1426.x
Percentiles
Phase 1 Patients
(n=137) 5th 25th 50th 75th 95th

AUCserum 5.667 6.636 7.265 8.213 17.042
AUCcolon wal 1.450 5.178 9.663 41.100 72.540
Penetration Ratio 0.183 0.654 1.300 3.937 6.839
Phase 2/3
Patients (n=303) 5th 25h 50th 75th 95th

AUCserum 5.554 6.196 6.914 8.124 13.265
AUCcolon wal 3.790 7.856 16.441 25.087 39.194
Penetration Ratio 0.476 0.852 2.553 3.651 5.709
Phase 1 Patients
(n=13) 5th 25th 50th 75th 95th

AUCserum 2.39 3.383 4.33 5.486 7.775
AUGELF 0.14 0.653 1.848 5.58 27.368
Penetration Ratio 0.035 0.156 0.433 1.243 6.013