Table 3.

GLP requirements for diagnostic EM

Lab organization	Technical facilities
Lab is part of a diagnostic network with efficient informational exchange (e.g. public health network or big clinic)	Working facilities according to safety regulations
Regularly trained personnel	Electron microscope with appropriate primary magnification
Data recording system	Low speed centrifuge for clearing
Controlled lab data flow	Ultracentrifuge for enrichment
	Stable highly adsorptive grids
	Different contrasting ‘stains’
	Panel of high affinity antibodies directed against diagnostic relevant viruses