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. 2019 Jan 17;158:61–68. doi: 10.1016/j.ymeth.2019.01.005

Table 2.

NxTAG RPP clinical performance before discrepant analysis (prospective sample Set).

Target Positive Agreement (Sensitivity)
Negative Agreement (Specificity)
# “No Call” by Comparator
TP/TP + FN % 95% CI TN/TN + FP % 95% CI
Influenza A (matrix) 259/273 94.9 91.5–97.2 1822/1859 98.0 97.3–98.6 0
Influenza A H1 21/21 100 83.9–100 2091/2111 99.1 98.5–99.4 0
Influenza A H3 203/206 98.5 95.8–99.7 1872/1917 97.7 96.9–98.3 9
Influenza B 87/91 95.6 89.1–98.8 2019/2033 99.3 98.8–99.6 8
Respiratory syncytial virus A 73/73 100 95.1–100 2037/2052 99.3 98.8–99.6 7
Respiratory syncytial virus B 131/133 98.5 94.7–99.8 1978/1990 99.4 98.9–99.7 9
Respiratory syncytial virus A & B (combined) 204/206 99.0 96.5–99.7 4015/4042 99.3 99.0–99.5 16
Coronavirus 229E 21/21 100 83.9–100 2098/2111 99.4 98.9–99.7 0
Coronavirus OC43 30/31 96.8 83.3–99.9 2092/2101 99.6 99.2–99.8 0
Coronavirus NL63 62/65 95.4 87.1–99.0 2053/2065 99.4 99.0–99.7 2
Coronavirus HKU1 13/14 92.9 66.1–99.8 2113/2118 99.8 99.4–99.9 0
All coronaviruses (combined) 126/131 96.2 91.4–98.4 8356/8395 99.5 99.4–9.7 2
Human metapneumovirus 135/144 93.8 88.5–97.1 1958/1976 99.1 98.6–99.5 12
Enterovirus/Rhinovirus 286/300 95.3 92.3–97.4 1764/1832 96.3 95.3–97.1 0
Adenovirus 20/20 100 83.2–100 2078/2112 98.4 97.8–98.9 0
Parainfluenza 1 5/5 100 47.8–100 2115/2116 99.9 99.7–100 11
Parainfluenza 2 1/2 50.0 1.3–98.7 2121/2122 99.9 99.7–100 8
Parainfluenza 3 20/21 95.2 76.2–99.9 2086/2103 99.2 98.7–99.5 8
Parainfluenza 4 3/5 60.0 14.7–94.7 2116/2127 99.5 99.1–99.7 0
Human bocavirus 27/28 96.4 81.7–99.9 2081/2104 98.9 98.4–99.3 0
Chlamydophila pneumoniae 0/1 0.0 0.0–97.5 2131/2131 100 99.8–100 0
Mycoplasma pneumoniae 7/9 77.8 40.0–97.2 2121/2123 99.9 99.7–100 0