Table 3.

NxTAG RPP performance after discrepant analysis (prospective sample set).

Target	Positive Agreement (Sensitivity)			Negative Agreement (Specificity)			# “No Call” by Comparator
	TP/TP + FN	%	95% CI	TN/TN + FP	%	95% CI
Influenza A (matrix)	271/271	100	98.6–100	1836/1860	98.0	98.1–99.1	0
Influenza A H1	21/21	100	83.9–100	2091/2111*	99.1	98.5–99.4	0
Influenza A H3	237/238	96.6	97.7–99.9	1874/1885	99.4	98.9–99.7	9
Influenza B	91/92	98.9	94.1–99.8	2022/2032	99.5	99.1–99.7	8
Respiratory syncytial virus A	81/81	100	95.1–100	2037/2044	99.7	99.3–99.8	7
Respiratory syncytial virus B	134/136	98.5	94.8–99.6	1978/1987	99.5	99.2–99.8	9
Coronavirus 229E	21/21	100	83.9–100	2098/2111	99.4	98.9–99.7	0
Coronavirus OC43	30/31	96.8	83.3–99.9	2092/2101	99.6	99.2–99.8	0
Coronavirus NL63	62/65	95.4	87.1–99.0	2053/2065	99.4	99.0–99.7	2
Coronavirus HKU1	13/14	92.9	66.1–99.8	2113/2118	99.8	99.4–99.9	0
Human metapneumovirus	137/140	97.9	93.9–99.3	1964/1980	99.2	98.7–99.5	12
Enterovirus/Rhinovirus	304/310	98.1	95.8–99.1	1772/1822	97.3	96.4–97.9	0
Adenovirus	22/22	100	85.1–100	2078/2110	98.5	97.9–98.9	0
Parainfluenza 1	5/5	100	47.8–100	2115/2116	99.9	99.7–100	11
Parainfluenza 2	1/1	100	20.7–100	2122/2123	99.9	99.7–100	8
Parainfluenza 3	22/22	100	85.1–100	2087/2102	99.3	98.8–99.6	8
Parainfluenza 4	3/5	60.0	14.7–94.7	2116/2127	99.5	99.1–99.7	0
Human bocavirus†	27/28	96.4	81.7–99.9	2081/2104	98.9	98.4–99.3	0
Chlamydophila pneumoniae†	0/1	0.0	0.0–97.5	2131/2131	100	99.8–100	0
Mycoplasma pneumoniae†	7/9	77.8	40.0–97.2	2121/2123	99.9	99.7–100	0

^*11/20 NxTAG RPP false positive specimens were un-subtypeable by the comparator. xTAG RVP does not detect influenza A(H1N1)pdm09 whereas NxTAG RPP does.

^†Discrepant analysis not available.