Table 1.

Characteristics of BioFire FilmArray RP, Nanosphere Verigene RV+ Test and Hologic Gen-Probe Prodesse assays

Name	BioFire FilmArray	Verigene	GenProbe Prodesse
Technology	Melting curve analysis	Gold nanoparticles with silver signal amplification	Melting curve analysis
Assays	Respiratory panel	Respiratory virus plus test	ProFlu+, ProFAST+, ProAdeno+, ProParaflu+, Pro hMPV+
Targets	•Adenovirus •Coronavirus HKU1 •Coronavirus NL63 •Coronavirus 229E •Coronavirus OC43 •hMPV •Human Rhinovirus/enterovirus •FluA •FluA/H1 •FluA/H3 •FluA/H1–2009 •Influenza B •Parainfluenza virus 1 •Parainfluenza virus 2 •Parainfluenza virus 3 •Parainfluenza virus 4 •RSV	•FluA-H1 •FluA-2009 H1N1 •FluA-H3 •FluA •Influenza B •RSV A •RSV B	•ProFlu+: FluA, influenza B, RSV •ProFAST+: Seasonal FluA/H1, seasonal FluA/H3, 2009 H1N1 influenza •ProAdeno+: Adenovirus •ProParaflu+: Parainfluenza 1, parainfluenza 2, parainfluenza 3 •Pro hMPV+: hMPV
Throughput	1 sample per instrument	1 sample per processor	14 samples per run
Run time (hours)	1	<2.5	4–5
Hands-on time	2 minutes	5 minutes	1.5 hours
Sample preparation included?	Yes	Yes	No
Reagent storage conditions	Room temperature	2–8°C and −20°C	−70°C

FluA, influenza A virus; hMPV, human metapneumovirus; RSV, respiratory syncytial virus.