Table 3.
Comparison among demographic data, underlying medical conditions, clinical manifestations, and laboratory findings of patients with acute respiratory disease and pneumonia caused by SARS-CoV-2.
Acute respiratory disease, N = 970 | Pneumonia, N = 468 | p value | |
---|---|---|---|
Sex | 0.3824 | ||
Male | 561 (57.8) | 282 (60.3) | |
Female | 409 (42.2) | 186 (39.7) | |
Age, years | 45.1 (17.3) | 53.1 (27.6) | <0.0001 |
Smoking | 122 (12.6) | 43/231 (18.6) | 0.0166 |
Comorbidities | |||
Hypertension | 129 (13.3) | 96/369 (26.0) | <0.0001 |
Diabetes mellitus | 55 (5.7) | 53/369 (14.4) | <0.0001 |
Chronic liver disease | 22/926 (2.4) | 2/214 (0.9) | 0.2883 |
COPD | 8 (0.8) | 15 (3.2) | 0.0007 |
Chronic kidney disease | 5/926 (0.5) | 7/311 (2.3) | 0.0143 |
Malignancy | 7/926 (0.8) | 15/451 (3.3) | 0.0004 |
Presentation | |||
Fever | 434 (44.7) | 357 (76.3) | <0.0001 |
Cough | 647 (66.7) | 330 (70.5) | 0.1467 |
Sputum production | 322 (33.2) | 120/369 (32.5) | 0.8143 |
Myalgia/fatigue | 156 (16.1) | 236 (50.4) | <0.0001 |
Dyspnea | 143 (14.7) | 167 (35.7) | <0.0001 |
Headache | 142 (14.6) | 49 (10.5) | 0.0291 |
Sore throat | 136 (14.0) | 56/427 (13.1) | 0.6506 |
Nausea or vomiting | 46 (4.7) | 34/427 (8.0) | 0.0170 |
Diarrhea | 36 (3.7) | 28 (6.0) | 0.0503 |
White blood cell, ×109/L | 4.9 (1.6) | 5.3 (3.2) | 0.0109 |
Neutrophil | 2.6 (1.1)/44 | 4.4 (3.3)/295 | <0.0001 |
Lymphocyte | 1.1 (0.5) | 0.8 (0.4) | <0.0001 |
Treatment | |||
Oxygen therapy | 314 (32.4) | 332 (70.9) | <0.0001 |
Ventilator | 0 (0.0) | 135 (28.8) | <0.0001 |
Renal replacement therapy | 0 (0.0) | 23/451 (5.1) | <0.0001 |
ECMO | 0 (0.0) | 14/451 (3.1) | <0.0001 |
Antibiotic therapy | 505 (52.1) | 264/330 (80.0) | <0.0001 |
Antiviral therapy | 336 (34.6) | 229 (48.9) | <0.0001 |
Outcome | |||
Discharged | 53 (5.5) | 111 (23.7) | <0.0001 |
Remained hospitalized | 916 (94.4) | 313 (66.5) | <0.0001 |
Died | 1 (0.1) | 37/451 (8.2) | <0.0001 |
Data are n (%), n/N (%), and mean (SD).
COPD, chronic obstructive pulmonary disease; ECMO, extracorporeal membrane oxygenation; NA, not available.
Bold indicates p < 0.05.