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. 2020 Mar 4;53(3):404–412. doi: 10.1016/j.jmii.2020.02.012

Table 3.

Comparison among demographic data, underlying medical conditions, clinical manifestations, and laboratory findings of patients with acute respiratory disease and pneumonia caused by SARS-CoV-2.

Acute respiratory disease, N = 970 Pneumonia, N = 468 p value
Sex 0.3824
 Male 561 (57.8) 282 (60.3)
 Female 409 (42.2) 186 (39.7)
Age, years 45.1 (17.3) 53.1 (27.6) <0.0001
Smoking 122 (12.6) 43/231 (18.6) 0.0166
Comorbidities
 Hypertension 129 (13.3) 96/369 (26.0) <0.0001
 Diabetes mellitus 55 (5.7) 53/369 (14.4) <0.0001
 Chronic liver disease 22/926 (2.4) 2/214 (0.9) 0.2883
 COPD 8 (0.8) 15 (3.2) 0.0007
 Chronic kidney disease 5/926 (0.5) 7/311 (2.3) 0.0143
 Malignancy 7/926 (0.8) 15/451 (3.3) 0.0004
Presentation
 Fever 434 (44.7) 357 (76.3) <0.0001
 Cough 647 (66.7) 330 (70.5) 0.1467
 Sputum production 322 (33.2) 120/369 (32.5) 0.8143
 Myalgia/fatigue 156 (16.1) 236 (50.4) <0.0001
 Dyspnea 143 (14.7) 167 (35.7) <0.0001
 Headache 142 (14.6) 49 (10.5) 0.0291
 Sore throat 136 (14.0) 56/427 (13.1) 0.6506
 Nausea or vomiting 46 (4.7) 34/427 (8.0) 0.0170
 Diarrhea 36 (3.7) 28 (6.0) 0.0503
White blood cell, ×109/L 4.9 (1.6) 5.3 (3.2) 0.0109
 Neutrophil 2.6 (1.1)/44 4.4 (3.3)/295 <0.0001
 Lymphocyte 1.1 (0.5) 0.8 (0.4) <0.0001
Treatment
 Oxygen therapy 314 (32.4) 332 (70.9) <0.0001
 Ventilator 0 (0.0) 135 (28.8) <0.0001
 Renal replacement therapy 0 (0.0) 23/451 (5.1) <0.0001
 ECMO 0 (0.0) 14/451 (3.1) <0.0001
 Antibiotic therapy 505 (52.1) 264/330 (80.0) <0.0001
 Antiviral therapy 336 (34.6) 229 (48.9) <0.0001
Outcome
 Discharged 53 (5.5) 111 (23.7) <0.0001
 Remained hospitalized 916 (94.4) 313 (66.5) <0.0001
 Died 1 (0.1) 37/451 (8.2) <0.0001

Data are n (%), n/N (%), and mean (SD).

COPD, chronic obstructive pulmonary disease; ECMO, extracorporeal membrane oxygenation; NA, not available.

Bold indicates p < 0.05.