Reference	Objective	Design	Evidence
Flanders et al. [227]	To evaluate the performance of a rapid, bedside whole blood C‐reactive protein test as a diagnostic test for pneumonia in adults	PCS	4A+
Hopstaken et al. [225]	To assess the diagnostic value of symptoms, signs, erythrocyte sedimentation rate (ESR), and C‐reactive protein (CRP) for pneumonia	PCS	4A+
Van de Meer et al. [229]	To evaluate the diagnostic accuracy of C‐reactive protein in detecting radiologically proved pneumonia and to evaluate how well it can discriminate between bacterial and viral infections of the lower respiratory tract.	MA	1A?
Graffelman et al. [226]	To assess the diagnostic value of signs, symptoms and CRP in detecting pneumonia	PCS	3B+
Holm et al. [228]	To evaluate the diagnostic value of CRP and procalcitonine in detecting pneumonia	PCS	3A+
Falk and Fahey [230]	To assess the diagnostic value of CRP in detecting pneumonia	MA	1A?