Table 1.

Admission characteristics of 176 episodes of fever and neutropenia in children with a demonstrated respiratory viral infection, according to intervention

Characteristics	Type of intervention		p
	Maintain antimicrobial	Antimicrobial withholding
	n = 92	n = 84
Age in years, median (IQR)	5 (3–9)	4 (3–8)	0.57
Male gender, n (%)	40 (44)	46 (55)	0.13
Type of cancer, n (%)
Leukaemia/Lymphoma	49 (53)	55 (66)	0.09
Leukaemia relapse	7 (8)	4 (5)	0.43
Solid tumours	36 (39)	25 (29)	0.19
High risk for invasive bacterial infection, n (%)	43 (47)	45 (54)	0.36
Use of G-CSF, n (%)	27 (29)	26 (31)	0.81
Use of CVC, n (%)	77 (84)	68 (81)	0.63
Hours of fever previous to admission, median (IQR)	2 (1–4)	2 (1–3)	0.10
Admission clinical diagnosis, n (% )
Fever without focus	19 (20)	13 (16)	0.37
Upper respiratory infection	42 (46)	44 (52)	0.37
Lower respiratory infection	23 (25)	22 (26)	0.85
Intestinal focus	6 (7)	5 (6)	0.87
Othersa	2 (2)	0

G-CSF: granulocyte-colony stimulating factor; CVC: central venous catheter; IQR: Interquartile range

^aOthers: Skin/soft tissue infection