Table 3.

Metals reported side effects.

Metal	Derivatives	Main cause of exposure	Side effects
Mercury	Methyl mercury	Skin ointments Dental amalgam fillings	Kidney disease [71]; peripheral neuropathy; multiple sclerosis [72]; ANA positivity [73]
		Polluted fish
	Thimerosal and phenyl mercury	Antiseptics/preservatives in eye drops vaccines	Flu like symptoms Eyelid eczema and edema
Gold	Colloidal gold [74]	Treatment for RA	Nephropathy
Nickel [75], [76]		Food Jewelry Tobacco	allergic and autoimmune symptoms; scleroderma-related autoantibodies and cutaneous sclerosis
Aluminum [4], [77]		Food Vaccines	Neurotoxic; delayed type hypersensitivity; ASIA syndrome; chronic fatigue syndrome; macrophagic myofasciitis

RA: rheumatoid arthritis.