Fig. 1.

Crystal structures of two SVMPs – atragin and K-like from Naja atra. The overall architectures of atragin and K-like from Naja atra are presented with metalloprotease domains aligned in the similar orientation. Both SVMP structures contain an M (yellow), a linker domain (pink), a D (blue), and a C (green) domain. N-glycans are colored in cyan. Gray spheres represent zinc ions and orange spheres represent calcium ions located at Ca(I):E208/D292/N398, Ca(II):N413/D417/E420/D423, and Ca(III):D474/E477/D489. A black line represents the missing loop containing the conserved Met-turn in the atragin structure.