Table 2.
Selected lncRNAs that are associated with CCA progression and function as ceRNAs
| lncRNA | Sample source | Upregulated or downregulated | Primary target | Secondary target | Association |
|---|---|---|---|---|---|
| KCNQ1OT1 (70) | 62 CCA tissues | Upregulated | miR-140 | SOX4 | Poor survival rates of patients |
| LMCD1-AS1 (71) | 20 CCA tissues | Upregulated | miR-345 | COL6A3 | CCA cell proliferation in vitro |
| LOXL1-AS1 (72) | 64 CCA tissues | Upregulated | miR-324-3p | ABCA1 | Poor survival rates of patients |
| NNT-AS1 (73) | 48 CCA tissues | Upregulated | miR-485 | BCL9 | Poor survival rates of patients |
| SNHG1 (125) | CCA cell lines | Upregulated | miR-140 | TLR4 | Tumor volume in xenograft mice |
| UCA1 (126) | 66 CCA tissues | Upregulated | miR-122 | Undefined | Poor survival rates of patients |
| Lnc-ATB (127) | 30 CCA tissues | Upregulated | miR-200c | CCND1/CDK2 | Tumor size and TNM stage of patients |
| MEG3 (128) | 20 CCA tissues | Downregulated | miR-361 | TRAF3 | Cell viability in vitro |
| SPRY4-IT1 (129) | 70 CCA tissues | Upregulated | miR-101-3p | EZH2 | Poor survival rates of patients |
| ZFAS1 (130) | 64 CCA tissues | Upregulated | miR-296 | USF1 | Poor survival rates of patients |