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. 2004 Jan 6;10(1):5–11. doi: 10.1111/j.1469-0691.2004.00699.x

Table 1.

Bottlenecks in molecular diagnostics

Problem identified Possible solution
1. Quantitative techniques Real‐time amplification techniques
2. Internal and external control Well defined universal internal controls (PhHV, PDV)
Quality control programmes
3. Sample preparation still matrix dependent New extraction techniques
4. Hands‐on time and turnaround time results Automation
5. Commercially interesting viruses vs. 
  viruses of no commercial interest Well characterised home‐brew assays