Table 2.
Laboratory findings from 621 hospitalized children infected with different HAdV genotypes
| Laboratory data | HAdV-2, n (%) |
HAdV-3, n (%) |
HAdV-7, n (%) |
p |
|---|---|---|---|---|
| Case number | 58 | 422 | 141 | |
| Haemogram | ||||
| WBC count (1000/μL)a | 15.36±5.85 | 12.93±5.48 | 9.39±4.69 | <0.001 |
| Peak or nadirb WBC count | 15.80±5.74 | 13.19±5.55 | 9.92±5.00 | <0.001 |
| <5000/μL | 0 | 7 (1.7) | 17 (12.1) | <0.001 |
| >15 000/μL | 28 (48.3) | 117 (27.7) | 18 (12.7) | <0.001 |
| Hb, mean±SD (g/dl) | 13.51±5.63 | 9.92±5.00 | 12.69±5.69 | 0.126 |
| Platelet, mean±SD (1000/μL) | 297.74±101.05 | 249.58±72.74 | 213.74±76.21 | <0.001 |
| <150 000/μL | 0 | 12 (2.8) | 22 (15.6) | <0.001 |
| >450 000/μL | 4 (6.9) | 8 (1.9) | 1 (0.7) | <0.001 |
| Biochemistry | ||||
| CRP (mg/L)a | 42.87±37.07 | 77.81±56.39 | 38.46±37.86 | <0.001 |
| Peak CRP (mg/L)b | 46.75±38.97 | 84.47±55.15 | 44.83±39.76 | <0.001 |
| <40 mg/L | 30 (51.7) | 93 (22.0) | 75 (53.2) | <0.001 |
| >100 mg/L | 7 (12.1) | 153 (36.3) | 14 (9.9) | <0.001 |
| BUN, mean±SD (mg/dL) | 8.99±3.54 | 7.84±3.55 | 8.52±5.78 | 0.463 |
| Cr, mean±SD (mg/dL) | 0.33±0.10 | 0.37±0.11 | 0.62±1.79 | 0.146 |
| >1.0 mg/dL | 2/24 (8.3) | 5/176 (2.8) | 7/66 (10.6) | 0.043 |
| AST (U/L) | 50.91±79.06 | 41.02±66.22 | 57.97±57.66 | 0.104 |
| >3-fold of normal value | 0/33 | 0/250 | 3/88 (3.4) | 0.008 |
Abbreviations: AST, aspartate aminotransferase; BUN, blood urea nitrogen; Cr, creatinine; CRP, C-reactive protein; HAdV, human adenovirus; Hb, haemoglobin; WBC, white blood cell;.
Note: Haemogram and CRP were checked in all 621 cases. Cr was checked in 266 cases (HAdV-2: 24 cases; HAdDV-3: 176 cases; and HAdV-7: 66 cases) and AST was checked in 371 cases (HAdV-2: 24 cases; HAdDV-3: 176 cases; and HAdV-7: 66 cases).
a
First laboratory examination on admission.
b
The highest or lowest laboratory value during hospitalization.